(buf′ə·lō) noun plural ·loes or ·los
1. A large Old World ox, now extensively domesticated, one of which, the African Cape buffalo (Syncerus caffer), has horns that broaden at the base. ◆ Collateral adjective: bubaline.
2. The Indian water buffalo.
3. The North American bison.
4. A buffalo robe.
5. A buffalo fish.
6. Naut. One of the bulwarks on each side of the stem of the forecastle deck in the extreme bow.
— v.t. U.S. Slang To overawe; hoodwink. [<Ital. <L bufalus, var. of bubalus <Gk. boubalos buffalo. Related to BUBAL.]

(buf′ə·lō)
A city in western New York at the eastern end of Lake Erie.